Proviron 5mg

$25.00

Chemical Information and Compositions of Proviron 5mg

For researchers, biochemists, and wholesale distributors, the molecular structure of Proviron 5mg is a classic example of targeted DHT modification. Understanding its composition is vital for analytical testing, formulation, and predicting its biological behavior.

Official Chemical Nomenclature

  • Chemical Name: 1α-Methyl-17β-hydroxy-5α-androstan-3-one; 1α-methyl-4,5α-dihydrotestosterone
  • Chemical Formula: C20H32O2
  • Molecular Weight: 304.47 g/mol
  • CAS Number: 1424-00-6

Structural Composition Breakdown

Proviron 5mg is a synthetic derivative of Dihydrotestosterone (DHT). Its structural architecture features a specific modification that defines its entire pharmacological profile:

  1. The DHT Base (5α-Reduced): The molecule is built upon the DHT skeleton. This means it is already 5-alpha reduced. It cannot be converted by the 5-alpha reductase enzyme into a more potent androgen (because it is already at maximum androgenic potency for this structural line). Crucially, because it is a DHT derivative, it cannot aromatize into estrogen. It has zero interaction with the aromatase enzyme.
  2. The 1α-Methyl Group: This is the defining structural modification. The addition of a methyl group at the 1-alpha position does two critical things:
    • Oral Bioavailability: Unlike base DHT, which is rapidly destroyed by the liver, the 1α-methyl group provides significant resistance to hepatic first-pass metabolism. Remarkably, it achieves this without the notorious 17-alpha-alkylation (17aa) used by steroids like Dianabol or Winstrol. This makes Proviron 5mg vastly less hepatotoxic than virtually all other oral steroids.
    • High SHBG Affinity: The 1α-methyl group induces a stereochemical conformation that gives the molecule an extraordinarily high binding affinity for Sex Hormone-Binding Globulin (SHBG).

Physical and Chemical Properties

  • State at Room Temperature: Solid (Crystalline Powder)
  • Color: White to off-white
  • Solubility: Practically insoluble in water; freely soluble in chloroform, DMSO, ethyl oleate, and ethanol.
  • Melting Point: Approximately 205°C to 210°C.

Pharmacokinetics

  • Route of Administration: Oral
  • Absorption: Rapidly and almost completely absorbed from the gastrointestinal tract.
  • Half-Life: The elimination half-life of Proviron 5mg is approximately 12 to 13 hours. This relatively short half-life necessitates twice-daily dosing to maintain stable blood plasma levels and continuous SHBG occupancy.
  • Metabolism: Metabolized in the liver via oxidation and conjugation, but the 1α-methyl group protects it from rapid destruction.
  • Excretion: Excreted primarily in the urine as inactive metabolites.

Formulation Details: The 5mg Pill

When you source wholesale Proviron 5mg, you are dealing with a micro-dose formulation. 5mg equals 0.005 grams.

Because 5mg is a very small mass, it must be geometrically diluted with excipients to create a uniform, handleable pill. Standard excipients include:

  • Lactose Monohydrate: Diluent.
  • Microcrystalline Cellulose (MCC): Binder/filler.
  • Croscarmellose Sodium: Disintegrant.
  • Magnesium Stearate: Lubricant.

For B2B buyers, ensuring the uniform blending of 5mg of Mesterolone API within the excipient matrix via geometric dilution is the most critical manufacturing challenge. Failure results in “hot spots” (pills with 15mg) and “dead spots” (pills with 0mg), which defeats the purpose of precise micro-dosing.

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