Clenbuterol 40mcg

$35.00

Chemical Information and Compositions of Clenbuterol 40mcg

For researchers, biochemists, and wholesale distributors, the molecular structure of Clenbuterol 40mcg is a classic example of targeted beta-2 agonist design. Understanding its composition is vital for analytical testing, formulation, and predicting its biological behavior.

Official Chemical Nomenclature

  • Chemical Name: (RS)-1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol hydrochloride
  • Chemical Formula: C12H18Cl2N2O · HCl (as the Hydrochloride salt)
  • Molecular Weight: 277.19 g/mol (Base); 313.65 g/mol (Hydrochloride salt)
  • CAS Number: 21898-19-1

Structural Composition Breakdown

Clenbuterol 40mcg is a substituted phenylethanolamine. Its structural architecture is what gives it its high beta-2 selectivity and its long biological half-life:

  1. The Dichlorophenyl Ring: The molecule features a phenyl ring substituted with an amino group at the para position and chlorine atoms at the 3 and 5 positions. The 3,5-dichloro substitution is critical; it dramatically increases the molecule’s lipophilicity and its affinity for the beta-2 adrenergic receptor, while simultaneously protecting it from rapid metabolic degradation by COMT (catechol-O-methyltransferase) and MAO (monoamine oxidase).
  2. The Ethanolamine Linkage: The two-carbon side chain connecting the aromatic ring to the amine group is characteristic of all beta-agonists. The hydroxyl group on the beta-carbon is essential for agonist activity.
  3. The Tert-Butyl Amine Group: Unlike epinephrine or ephedrine which have smaller amine substituents, Clenbuterol features a bulky tert-butyl group on the nitrogen. This massive steric bulk is the primary driver of its beta-2 receptor selectivity. It physically prevents the molecule from fitting into the binding pocket of alpha-receptors and beta-1 receptors (which primarily control heart rate), forcing it to bind preferentially to beta-2 receptors (which control bronchodilation and lipolysis).

Physical and Chemical Properties

  • State at Room Temperature: Solid (Crystalline Powder)
  • Color: White or almost white
  • Solubility: Freely soluble in water and ethanol; slightly soluble in chloroform; practically insoluble in ether. Its high water solubility as a hydrochloride salt makes it highly bioavailable upon oral ingestion.
  • Melting Point: Approximately 174°C to 175.5°C (with decomposition).

Pharmacokinetics

  • Route of Administration: Oral
  • Absorption: Rapidly and almost completely absorbed from the gastrointestinal tract.
  • Half-Life: The biological half-life of Clenbuterol 40mcg in humans is exceptionally long—approximately 34 to 35 hours. This is due to the dichloro-substitution which makes it highly resistant to hepatic first-pass metabolism. Because of this ultra-long half-life, the compound accumulates in the system with daily dosing, making side-effect management challenging and necessitating specific cycling protocols.
  • Metabolism: Partially metabolized in the liver, but largely excreted unchanged in the urine.
  • Elimination: Renal excretion is the primary route of clearance.

Formulation Details: The 40mcg Pill

When you source wholesale Clenbuterol 40mcg, you are dealing with one of the most challenging micro-doses in commercial pharmacology.

  • 40mcg equals 0.040 milligrams.
  • To put this in perspective, a standard tablet might weigh 200mg total, but only 0.04mg of that weight is the active Clenbuterol Hydrochloride. That means the API makes up only 0.02% of the total pill mass.

Standard excipients used to dilute and bind the API include:

  • Microcrystalline Cellulose (MCC): Filler and binder.
  • Lactose Monohydrate: Diluent to add necessary bulk.
  • Croscarmellose Sodium: Disintegrant.
  • Magnesium Stearate: Lubricant.

The geometric dilution required to ensure that every single pill contains exactly 40mcg—without “hot spots” that could trigger a cardiac event, or “dead spots” that provide zero therapeutic value—is the most critical manufacturing challenge for wholesale Clenbuterol 40mcg.